Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Respiratory sequelae and lung function after whooping cough in infancy.

I Krantz1, J Bjure, I Claesson

  • 1Department of Infectious Diseases, East Hospital, Göteborg, Sweden.

Archives of Disease in Childhood
|June 1, 1990
PubMed
Summary

Whooping cough in infancy does not appear to cause later obstructive respiratory disease in children. A cohort study found no significant lung function differences between children with and without a history of the illness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Streptozotocin plus 5-fluorouracil followed by everolimus or the reverse sequence in patients with advanced pancreatic neuroendocrine tumors (SEQTOR-GETNE phase III study): a randomized clinical trial.

ESMO open·2025
Same author

Learning from each other: Cross-cutting diagnostic development activities between magnetic and inertial confinement fusion (invited).

The Review of scientific instruments·2024
Same author

New method for time alignment and time calibration of the TOFOR time-of-flight neutron spectrometer at JET.

The Review of scientific instruments·2021
Same author

Histamine in gastric carcinoid tumors: Immunocytochemical evidence.

Endocrine pathology·2020
Same author

Electron-microscopical immunocytochemical study of a pancreatic islet amyloid polypeptidoma.

Endocrine pathology·2020
Same author

Antiserum directed against chromogranin A and B (CAB) is a useful marker for peptide hormone-producing endocrine cells and tumors.

Endocrine pathology·2020

Area of Science:

  • Pediatric Pulmonology
  • Infectious Disease Epidemiology

Background:

  • Whooping cough (pertussis) is a significant childhood illness.
  • Concerns exist regarding potential long-term respiratory consequences.
  • Previous research on post-pertussis lung function is limited.

Purpose of the Study:

  • To investigate the long-term effects of infant whooping cough on lung function in children.
  • To determine if a history of pertussis is associated with later obstructive airway disease.

Main Methods:

  • Community-based cohort study comparing 31 children with infant whooping cough to 32 matched controls.
  • Assessed lung function via spirometry before and after bronchodilator (salbutamol) and exercise challenges.
  • Evaluated family history, atopy, smoking, and respiratory infection history.

Related Experiment Videos

Main Results:

  • No significant differences in lung function parameters were observed between the whooping cough and control groups.
  • No impairment of small airways was detected in children with a history of pertussis.
  • Background factors, including family history of obstructive airway disease and atopy, were similar between groups.

Conclusions:

  • The study does not support the hypothesis that whooping cough in itself is a causal factor for later obstructive respiratory disease.
  • Infant pertussis infection does not appear to lead to measurable long-term lung function deficits or small airway impairment.