Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

CRISPR/Cas9 Genome Editing

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Engineering an Exo70 integrated domain of a barley NLR for improved blast resistance.

The Plant cell·2026

Same author

A potato late blight pathogen effector interacts with ENTH-domain protein TOL9a and an activated helper NLR to suppress immunity.

Science advances·2026

Same author

A plant pathogen effector blocks stepwise assembly of a helper NLR resistosome.

Science advances·2026

Same author

Molecular mimicry of a pathogen virulence target by a plant immune receptor.

Science (New York, N.Y.)·2026

Same author

A helper NLR channels organellar calcium to trigger plant immunity.

Science (New York, N.Y.)·2026

Same author

An activated wheat CC<sub>G10</sub>-NLR immune receptor forms an octameric resistosome.

Cell·2026

Search research articles

Related Experiment Video

Updated: May 10, 2026

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish

Published on: October 27, 2019

Hooked and cooked: a fish killer genome exposed

Mark J Banfield¹, Sophien Kamoun

¹Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, UK.

|June 21, 2013

Summary

No abstract available in PubMed .

More Related Videos

Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio

Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio

Published on: August 28, 2018

Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene Editing

Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene Editing

Published on: January 20, 2018

Related Experiment Videos

Last Updated: May 10, 2026

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish

Published on: October 27, 2019

Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio

Efficient Production and Identification of CRISPR/Cas9-generated Gene Knockouts in the Model System Danio rerio

Published on: August 28, 2018

Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene Editing

Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene Editing

Published on: January 20, 2018