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Updated: May 10, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Association between melanocytic neoplasms and seborrheic keratosis: more than a coincidental collision?
Jennifer Defazio1, Iris Zalaudek, Klaus J Busam
1Dermatology Service, Memorial Sloan-Kettering Cancer Center, Hauppauge, NY, USA.
Abstract:
Clinical observations and an expanding knowledge of cell-to-cell communication have led us to speculate that the finding of a melanocytic nevus in conjunction with a seborrheic keratosis is more than a coincidental collision of two lesions. Here we present five cases demonstrating dermoscopic features of both melanocytic lesions and seborrheic keratoses with corresponding histology. Four cases demonstrate dermoscopic features of a melanocytic nevus and seborrheic keratosis, and the final case a melanoma arising in association with a seborrheic keratosis.
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