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Updated: May 10, 2026

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Published on: March 30, 2018
Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma
Philipp Tschandl1, Leonhard Müllauer, Harald Kittler
1Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria.
Abstract:
A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis. A consequently performed bone marrow biopsy verified a systemic mastocytosis and a chronic myelomonocytic leukemia (CMML) type I. HERE, WE DESCRIBE FOR THE FIRST TIME IN THE LITERATURE A PATIENT WITH THREE DISEASES OCCURRING SYNCHRONOUSLY: CMML, xanthogranulomas and systemic mastocytosis. Two of them at a time are known to be associated and may be indicative of a common progenitor cell.
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