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Updated: May 10, 2026

Iridium(III) Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
A retrievable and highly selective fluorescent probe for monitoring dihydrogen phosphate ions based on a
Zhijun Chen1, Limin Wang, Gang Zou
1Shanghai Key Laboratory of Functional Materials Chemistry and Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, PR China.
Abstract:
A novel selective fluorescent chemosensor based on naphthalimide derivatives (AN-SB) was synthesized and characterized. Once combined with Cu(2+), compound AN-SB could give rise to a visible yellow to orange color change and fluorescence quenching, while other metal ions showed subtle disturbance. The complex (AN-SB-Cu(2+)) formed by Cu(2+) and AN-SB displayed high specificity for H2PO4(-). Among the various anions, only H2PO4(-) induced the revival of color and fluorescence of AN-SB, resulting in "off-on" type sensing of H2PO4(-) anion. The signal transduction occured via reversible formation-separation of complex AN-SB-Cu(2+), however, slight changes were observed in the presence of other anions.
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