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Preparation of Food Samples Using Homogenization and Microwave-Assisted Wet Acid Digestion for Multi-Element Determination with ICP-MS
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Applications of monolithic materials for sample preparation
Tarang Nema1, Eric C Y Chan, Paul C Ho
1Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore; Waters Pacific Pte. Ltd., 1 Science Park Road, Singapore Science Park II, Singapore 117528, Singapore.
Journal of Pharmaceutical and Biomedical Analysis
|June 22, 2013
Summary
Monolithic columns offer advantages over traditional packed columns in chromatography and capillary electrochromatography (CEC). This review highlights their latest developments, especially for analytical sample preparation.
Area of Science:
- Analytical Chemistry
- Chromatography
Background:
- Monolithic columns are emerging as a viable alternative to traditional packed columns in liquid chromatography and capillary electrochromatography (CEC).
- These columns offer several advantages, driving extensive research into their preparation, characterization, and applications.
- A significant body of literature demonstrates their potential as substitutes for particle-packed columns.
Purpose of the Study:
- To review recent advancements in monolithic column technology for analytical chemistry.
- To emphasize the application of monoliths in sample preparation, a critical step in analytical workflows.
Main Methods:
- Literature review of recent developments in monolithic column technology.
- Focus on preparation techniques, characteristic evaluations, and diverse applications.
- Specific emphasis on the role of monoliths in sample preparation.
Main Results:
- Monolithic columns present a promising alternative to packed columns due to their inherent advantages.
- Ongoing research continuously refines their preparation and characterization.
- Applications span various analytical chemistry modes, with a notable focus on sample preparation.
Conclusions:
- Monolithic columns are increasingly recognized as effective alternatives in chromatographic and CEC analyses.
- Their application in sample preparation is a key area of development, enhancing analytical efficiency.
- Continued research promises further innovation in monolithic column technology for analytical chemistry.
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