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Updated: May 10, 2026

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model
Published on: December 10, 2021
Associations of particulate matter with stroke mortality: a multicity study in Japan
Takashi Yorifuji1, Saori Kashima
1Department of Human Ecology, Okayama University Graduate School of Environmental and Life Science, Kita-ku, Okayama, Japan. yorichan@md.okayama-u.ac.jp
Objective:
Evidence linking short-term exposure to outdoor air pollution with hemorrhagic stroke is inconclusive.
Methods:
We evaluated the effects of suspended particulate matter (SPM) on cardiovascular disease mortality, focusing on types of stroke, from March 2005 to December 2010, in five selected prefectures in western Japan. A multicity time-series analysis was used, and Asian dust was adjusted in the models.
Results:
Even after adjusting for Asian dust, the same-day SPM was positively associated with several types of stroke mortality. Following a 10-μg/m increase in SPM, rate ratios were 1.014 (90% confidence interval [CI]: 1.002 to 1.026) for stroke, 1.030 (90% CI: 1.004 to 1.056) for intracerebral hemorrhage, and 1.016 (90% CI: 1.003 to 1.030) for ischemic stroke mortality.
Conclusions:
Short-term exposure to outdoor air pollution may increase the risks of hemorrhagic stroke as well as ischemic stroke mortality.
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