Characteristics and outcomes of liver and lung hydatid disease in children

Muazez Çevik1, Irfan Eser, Mehmet Emin Boleken

  • 1Faculty of Medicine, Department of Pediatric Surgery, Harran University, TR-63100, Sanliurfa, Turkey. cevikmuazzez@gmail.com

Tropical Doctor
|June 22, 2013
PubMed

Insights

Pediatric hydatid disease (HD) in the lungs presents more complications and symptoms than liver HD upon admission. This retrospective study analyzed 152 children diagnosed with liver and/or lung hydatid disease.

Area of Science:

  • Medical research
  • Pediatric infectious diseases
  • Parasitology

Background:

  • Hydatid disease (HD) is a parasitic infection caused by Echinococcus tapeworms.
  • It commonly affects the liver and lungs, particularly in endemic regions.
  • Understanding pediatric HD characteristics is crucial for timely diagnosis and management.

Purpose of the Study:

  • To retrospectively evaluate and compare the clinical characteristics of pediatric lung and liver hydatid disease.
  • To identify demographic trends and outcomes associated with HD in children.
  • To differentiate the presentation of lung versus liver involvement in pediatric HD.

Main Methods:

  • Retrospective analysis of medical records from 2007-2012.
  • Inclusion criteria: patients aged ≤17 years with confirmed liver and/or lung HD.
  • Data collected: demographics, clinical presentation, hospital stay, and outcomes.

Main Results:

  • A total of 252 cysts were identified in 152 pediatric patients.
  • HD incidence increased with age, with most patients >9 years old.
  • Lung HD was found to be more complicated and symptomatic at initial presentation compared to liver HD.

Conclusions:

  • Pediatric lung hydatid disease exhibits a more complex and symptomatic clinical course upon admission.
  • Age is a significant factor in the incidence of HD in children.
  • Further research into specific management strategies for pediatric lung HD is warranted.

Related Concept Videos

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...