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Updated: May 10, 2026

Multi-Gene Single Nucleotide Polymorphism Detection in Gastric Cancer Based on Ion Semiconductor Sequencing Platform
Published on: May 10, 2024
Chemotherapy for gastric cancer patients - time for personalization in medicine?
Elżbieta Nowara1, Agnieszka Boratyn-Nowicka, Anna Polakiewicz-Gilowska
1Clinical and Experimental Oncology Department, Cancer Centre - Institute of Oncology - MSC Gliwice Branch, Poland.
Abstract:
Gastric cancer is one of the most frequent neoplasms. Although the incidence of gastric cancer worldwide has declined, there is still high mortality. Treatment of inoperable disease is under evaluation in clinical trials. In palliative treatment chemotherapy containing cisplatin and 5-fluorouracil is the most widely used. In the past years progress in tumour biology has advanced greatly and has led to development of new molecules aimed at targets important for cancer expansion. There are several randomized trials under targeted therapies for gastric cancer patients. One of them led to approval of trastuzumab. In the current paper the authors illustrate new possibilities in systemic treatment with particular attention to targeted therapy and personalization in medicine.
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