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Fever of unknown origin: a clinical mask of malignant peritoneal mesothelioma

Jacek Hermann1, Grzegorz Bajko, Marek Stajgis

  • 1Department of General, Gastrointestinal and Endocrinological Surgery, Poznan University of Medical Sciences, Poznań, Poland.

Contemporary Oncology (Poznan, Poland)
|June 22, 2013
PubMed

Insights

Malignant peritoneal mesothelioma can present with fever of unknown origin, masking the disease. This case highlights the importance of considering malignancy in persistent pyrexia, even when infections are suspected.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Malignant peritoneal mesothelioma is a rare and aggressive cancer.
  • Accurate differential diagnosis is critical for patient management.

Observation:

  • The patient presented with fever of unknown origin, a less common symptom of mesothelioma.
  • Typical symptoms like abdominal pain, distension, anorexia, and ascites were also present.

Findings:

  • Fever of unknown origin can mimic infectious or autoimmune diseases.
  • Systemic inflammatory response syndrome (SIRS) can be triggered by various conditions, including malignancy.

Implications:

  • Clinicians should consider mesothelioma in the differential diagnosis of unexplained fever, especially with other suggestive symptoms.
  • Early and accurate diagnosis of malignant peritoneal mesothelioma is crucial for appropriate treatment and improved patient outcomes.
Keywords:
fever of unknown originmalignant peritoneal mesothelioma

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