Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...

Pulmonary Embolism I: Introduction

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of montelukast a leukotriene inhibitor on gastric cancer MGC803 cells.

Journal of toxicology and environmental health. Part A·2026

Same author

Programmable adenine base editing in cyanobacteria using an engineered TadA-Cas9 fusion.

The Plant journal : for cell and molecular biology·2026

Same author

Primary pelvic retroperitoneal smooth muscle tumor with cystic degeneration: a case report and review of the literature.

BMC women's health·2025

Same author

Correction: Experience of copy number variation sequencing applied in spontaneous abortion.

BMC medical genomics·2025

Same author

Molecular mechanism of a coastal cyanobacterium <i>Synechococcus</i> sp. PCC 7002 adapting to changing phosphate concentrations.

Marine life science & technology·2024

Same author

Development of a base editor for convenient and multiplex genome editing in cyanobacteria.

Communications biology·2024

Search research articles

Related Experiment Video

Updated: May 10, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Pulmonary sarcomatoid carcinoma: a case report.

Xiao-Yong Shen¹, Zhi-Feng Lin, Qiang Lin

¹Department of Thoracic Surgery, Huadong Hospital, Shanghai Fudan University, Shanghai, China ; The authors wish it to be known that in their opinion, the first two authors should be regarded as joint first authors.

Contemporary Oncology (Poznan, Poland)

|June 22, 2013

Summary

Sarcomatoid carcinoma (SC) is a rare cancer with both carcinomatous and sarcomatous elements. This case report details a pulmonary sarcomatoid carcinoma (PSC) diagnosis and treatment in a 75-year-old man.

Keywords:

carcinoma diagnosis lung neoplasms treatment

Related Experiment Videos

Last Updated: May 10, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Area of Science:

Oncology
Pathology

Background:

Sarcomatoid carcinoma (SC) is a rare malignant neoplasm characterized by the simultaneous presence of carcinomatous and sarcomatous components.
Pulmonary sarcomatoid carcinoma (PSC) is an uncommon subtype, often exhibiting spindle or giant cell morphology.

Observation:

A 75-year-old male presented with a six-month history of cough and hemoptysis.
Imaging revealed a left lung tumor involving the hilum and pulmonary artery.
Bronchoscopic brushing identified pleomorphic interstitial cells.

Findings:

A left pneumonectomy was performed for definitive diagnosis and treatment.
The patient was pathologically staged as IIB (pT2N1M0) using the TNM system.
The study discusses the tumor's pathology, histology, immunohistochemistry, and management.

Implications:

This case highlights the diagnostic challenges and treatment approaches for pulmonary sarcomatoid carcinoma.
Understanding the distinct pathological features is crucial for accurate staging and therapeutic decisions.
Further research into PSC is warranted due to its rarity and aggressive nature.