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[Efficiency of endoscopic treatment of primary vesicoureteral reflux depending on bulking agent]

F K Abdullaev, V D Kulaev, V V Nikolaev

    Urologiia (Moscow, Russia : 1999)
    |June 25, 2013
    PubMed

    Insights

    Endoscopic treatment for vesicoureteral reflux (VUR) in children showed varying success rates with different bulking agents. Vantris is recommended as a safe and effective option for VUR treatment.

    Area of Science:

    • Pediatric Urology
    • Minimally Invasive Surgery
    • Biomaterials in Medicine

    Background:

    • Vesicoureteral reflux (VUR) is a common condition in children.
    • Endoscopic treatment offers a minimally invasive approach to VUR management.
    • Various bulking agents have been utilized for endoscopic VUR correction.

    Purpose of the Study:

    • To compare the effectiveness of different bulking agents used in endoscopic treatment of primary VUR in children.
    • To evaluate the safety and efficacy of Teflon paste, DAM+, Urodex, and Vantris.
    • To identify the optimal bulking agent for VUR treatment in pediatric patients.

    Main Methods:

    • A retrospective study of over 4,000 children undergoing endoscopic VUR treatment from 1991 to 2011.
    • Comparative analysis of single endoplasty outcomes using Teflon paste, DAM+, Urodex, and Vantris.
    • Inclusion criteria: primary VUR (Grades I-V), absence of major ureteral abnormalities, and no chronic cystitis.

    Main Results:

    • Teflon paste achieved reflux elimination in 95.3% of cases (107 patients).
    • Vantris demonstrated a success rate of 92.9% (56 patients).
    • DAM+ and Urodex showed lower efficacy at 77.8% (186 patients) and 68.1% (69 patients), respectively.

    Conclusions:

    • Vantris is a highly effective bulking agent for endoscopic VUR treatment in children.
    • Vantris meets modern safety requirements, making it a recommended option.
    • The study highlights the importance of selecting appropriate bulking agents for successful VUR management.

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