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[Programme review of somatropin deficit in pediatrics at the Hospital Universitario Virgen del Rocío]
Insights
Growth hormone therapy (somatropin) effectively increased height in pediatric patients with growth hormone deficiency or born small for gestational age. Female patients aged 0-12 with growth hormone deficiency showed the best response in the first year.
Area of Science:
- Pediatric Endocrinology
- Growth Hormone Therapy
- Clinical Research
Context:
- Somatropin (growth hormone) is used to treat growth deficiencies in children.
- Assessing treatment effectiveness is crucial for optimizing pediatric care.
- This study reviews somatropin use at Hospital Universitario Virgen del Rocío.
Purpose:
- To review the effectiveness of somatropin treatment in pediatric patients.
- To compare outcomes in children with growth hormone deficiency versus those born small for gestational age.
- To evaluate treatment efficacy during the first year of therapy.
Summary:
- A retrospective, observational study analyzed pediatric patients receiving somatropin.
- Patients included those with growth hormone deficiency and those born small for gestational age.
- Growth rate increased, and bone age neared chronological age post-treatment.
Impact:
- Somatropin treatment demonstrated high effectiveness in both patient groups.
- A favorable increase in height was observed in treated children.
- Female patients aged 0-12 with growth hormone deficiency exhibited the most significant response.
Object:
To develop a program review of somatropin deficit, applied in pediatrics at the Hospital Universitario Virgen del Rocío, using two groups of patients: the ones diagnosed with deficiency of this hormone, and those born small for gestational age, with the intention of evaluating its effectiveness in the first year of treatment.
Method:
Attaining a retrospective study of the cohort of patients treated with growth hormone under the above diagnoses, with cross-sectional and observational methodology, to which we applied a statistical analysis with the Statistical Package for Social Sciences®.
Results:
After the beginning of the treatment, the growth rate had increased and the bone age approximated to the chronologic age. In the two treated groups in the first year of treatment were the female patients aged between 0 to 12 years with a deficit of growth hormone who responded better to therapy.
Conclusions:
We observed that the treatment instituted appeared highly effective in both groups of patients, allowing a favorable increase in height.
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