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Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
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Independent calculation-based verification of IMRT plans using a 3D dose-calculation engine.

Sankar Arumugam1, Aitang Xing, Gary Goozee

  • 1Liverpool and Macarthur Cancer Therapy Centres, New South Wales, Australia; The Ingham Institute, New South Wales, Australia.

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
|June 25, 2013
PubMed
Summary

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This study developed in-house software to transfer intensity-modulated radiation therapy (IMRT) plans between different treatment planning systems (TPS). The software enables accurate 3D dose verification, crucial for independent monitor unit checks in radiation oncology.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Imaging

Background:

  • Independent monitor unit verification of intensity-modulated radiation therapy (IMRT) plans is essential for patient safety.
  • Current treatment planning systems (TPS) often lack interoperability for direct IMRT plan transfer, hindering cross-system verification.
  • Accurate 3-dimensional (3D) dose verification is critical for ensuring the efficacy and safety of IMRT delivery.

Purpose of the Study:

  • To investigate the feasibility of using a 3D dose engine in a secondary TPS for IMRT plan verification.
  • To develop and validate in-house software for transferring IMRT plans between different TPS (XiO and Pinnacle).
  • To assess the accuracy of IMRT plan conversion and subsequent 3D dose verification.

Main Methods:

Keywords:
Dose-calculation algorithmsIMRTIndependent calculationTreatment planning system

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  • Developed in-house software to convert radiation therapy prescription (RTP) files into XiO and Pinnacle IMRT file formats.
  • Transferred 14 IMRT plans between XiO and Pinnacle TPS for independent 3D dose verification.
  • Compared 3D dose matrices and dose-volume histograms (DVHs) of original and recalculated plans using gamma analysis (3%/3mm).

    • Main Results:

    • The developed software successfully transferred IMRT plans between XiO and Pinnacle TPS.
    • Good agreement was observed for planning target volume (PTV) DVHs, with minor differences in mean dose, D95, and V95.
    • DVH comparisons for organs at risk showed acceptable agreement in high- and medium-dose regions, but notable differences in low-dose regions (<15% prescription dose).
    • Gamma analysis (3%/3mm) demonstrated high passing rates (mean >96%) for dose matrix comparisons across all planes, indicating accurate plan recalculation.

    Conclusions:

    • The in-house software effectively facilitates IMRT plan transfer between different TPS, enabling cross-platform 3D dose verification.
    • The developed method provides a viable solution for independent IMRT plan verification, enhancing quality assurance in radiation oncology.
    • While generally accurate, careful consideration of dose differences in low-dose regions is necessary when comparing plans across different TPS.