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Updated: May 10, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Catheter intervention for congenital heart disease at risk of circulatory failure
Adrian Dancea1, Henri Justino, Giuseppe Martucci
1Division of Cardiology, Montreal Children's Hospital, McGill University Health Center, Montreal, Québec, Canada. adrian.dancea@mcgill.ca
Insights
Percutaneous interventions offer effective treatments for heart failure in congenital heart disease patients. These minimally invasive procedures improve heart function by addressing issues like aortic stenosis and septal defects.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Congenital heart disease (CHD) can lead to heart failure due to ventricular overload or dysfunction.
- Systemic left ventricle failure may occur from increased afterload (e.g., aortic stenosis, coarctation) or large shunts (e.g., VSD, PDA).
- Postoperative right ventricle dysfunction is a risk in patients with residual obstruction or volume overload.
Purpose of the Study:
- To review the role of percutaneous interventions in managing heart failure secondary to congenital heart disease.
- To highlight the efficacy of catheter-based therapies in improving hemodynamics and ventricular function.
- To discuss current interventional strategies for various forms of pediatric heart failure.
Main Methods:
- Review of percutaneous techniques including balloon dilation, device closure, angioplasty, stenting, and valve implantation.
- Focus on interventions for aortic stenosis, coarctation, ventricular septal defects, patent ductus arteriosus, and pulmonary valve issues.
- Discussion of approaches for single ventricle physiology and hypoplastic left heart syndrome.
Main Results:
- Balloon dilation of aortic valves is safe and effective in neonates with critical aortic stenosis.
- Device closure of septal defects and patent ductus arteriosus is a viable option for selected infants.
- Pulmonary valve interventions and stenting effectively reduce right ventricular afterload.
- Percutaneously implantable pulmonary valves offer rehabilitation for dysfunctional conduits.
- Catheter interventions optimize hemodynamics in single ventricle patients.
Conclusions:
- Percutaneous interventions are crucial adjuncts in managing heart failure in pediatric CHD.
- These minimally invasive techniques provide effective solutions for various hemodynamic challenges in CHD.
- Optimized hemodynamic management through catheter interventions improves outcomes for complex congenital heart conditions.
Abstract:
Percutaneous interventions complement other therapeutic modalities in the management of patients with heart failure secondary to congenital heart disease. The systemic left ventricle can fail when submitted to excessive afterload as seen with critical aortic stenosis or coarctation. Balloon dilation of the aortic valve is safe and effective in establishing adequate forward flow and improving myocardial function in neonates. A large left-to-right shunt caused by a ventricular septal defect or a patent ductus arteriosus can lead to left ventricular failure. In selected infants, device closure of these defects is a therapeutic option. The postoperative right ventricle burdened by chronic residual obstruction and volume overload is at risk of failure. Balloon dilation of the pulmonary valve, pulmonary artery angioplasty with or without stent implantation, and pulmonary conduit stenting are effective in minimizing afterload to the right ventricle. More recently, percutaneously implantable pulmonary valves have become an option, in selected patients, for full rehabilitation of dysfunctional pulmonary conduits. Patients with single ventricle physiology have a fragile physiology, justifying an aggressive catheter interventional approach to optimize hemodynamic characteristics. The hybrid approach to palliation of hypoplastic left heart syndrome has become a viable option in selected centres.
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