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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

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Affective temperaments and psychotropic adherence.

Kimie Kamei¹, Takeshi Terao, Yosuke Katayama

¹Department of Neuropsychiatry, Oita University, Faculty of Medicine, Idaigaoka 1-1, Hasama-machi, Yufu-city, Oita 879-5593, Japan.

Journal of Affective Disorders

|June 25, 2013

Summary

Patients with irritable temperament may struggle with psychotropic medication adherence. Conversely, male patients and those with depressive or hyperthymic temperaments show better treatment attitudes.

Keywords:

Adherence DAI-10 Temperament VAS

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Area of Science:

Psychiatry
Psychopharmacology
Temperament Research

Background:

Adherence to psychotropic medications is influenced by various factors.
This study investigates the impact of affective temperaments on treatment adherence.

Purpose of the Study:

To examine the relationship between specific affective temperaments (depressive, hyperthymic, cyclothymic, irritable, anxious) and adherence to psychotropic medications.
To identify patient characteristics associated with better or poorer medication compliance.

Main Methods:

Utilized the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire version (TEMPS-A) to assess affective temperaments.
Employed the Drug Attitude Inventory-10 (DAI-10) for concordance and persistence, and the Visual Analogue Scale (VAS) for compliance.
Study included thirty-eight consecutive psychiatric inpatients.

Main Results:

Negative association found between irritable temperament scores and VAS scores for dose compliance.
Positive association observed between DAI-10 scores and male gender, depressive temperament, and hyperthymic temperament.
Irritable temperament linked to poorer treatment compliance.

Conclusions:

Patients with irritable temperament may require additional education to improve medication compliance.
Male patients and those with depressive or hyperthymic temperaments demonstrate a more positive attitude towards psychotropic medication.
Findings suggest affective temperaments play a role in psychotropic medication adherence.