Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TACTIC: A transfer learning framework to predict drug interactions in emerging pathogens.

Cell reports methods·2026
Same author

Growing Trends in the Payvider Model and US Hospital Systems Owning Health Plans.

JAMA·2026
Same author

Two-Year Burden of Antibiotic Use for Prosthetic Joint Infection Following Total Knee Arthroplasty.

Surgical infections·2026
Same author

Minimal Clinically Importance Difference and Substantial Clinical Benefit in Total Knee Arthroplasty: Delayed Achievers and Maintaining Improvement.

The Journal of arthroplasty·2026
Same author

Examining the racial and ethnic disparities in pediatric surgery using the surgical Desirability of Outcome Ranking (DOOR).

American journal of surgery·2025
Same author

National trends in total and unicompartmental knee arthroplasty: 2020 to 2022.

Journal of clinical orthopaedics and trauma·2025

Related Experiment Video

Updated: May 10, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

A practical index to predict 30-day mortality after major amputation.

Molly Crimmins Easterlin1, David C Chang, Samuel Eric Wilson

  • 1Department of Surgery, University of California San Diego, San Diego, CA 92103-8400, USA. mceaster@ucsd.edu

Annals of Vascular Surgery
|June 25, 2013
PubMed
Summary

A new clinical index helps identify patients at high risk of 30-day mortality after major amputation. Patients scoring 5 or higher need closer post-operative care or extended hospital stays.

Related Experiment Videos

Last Updated: May 10, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Area of Science:

  • Surgical outcomes research
  • Clinical risk prediction modeling

Background:

  • Identifying patients at risk of mortality after amputation is crucial for optimizing postoperative care.
  • Current methods for risk stratification in post-amputation patients are insufficient.

Purpose of the Study:

  • To develop and validate a clinical index for predicting 30-day mortality following major amputations.
  • To enable better stratification of postoperative care intensity based on predicted risk.

Main Methods:

  • Analysis of the National Surgical Quality Improvement Program (NSQIP) database (2005-2009).
  • Inclusion of patients undergoing above- or below-knee amputations.
  • Development of an additive risk index using logistic regression on demographics, comorbidities, and operative factors.

Main Results:

  • The study analyzed 9,244 patients, with an 8.1% 30-day mortality rate (744 deaths).
  • The final 11-component index (score range 0-13) includes factors like age, heart failure, COPD, steroid use, functional status, dyspnea, dialysis, impaired sensorium, and sepsis.
  • A score of 5 or higher was identified as a threshold for significant mortality risk (10% at score 5, 38.5% at score 10), with a c-statistic of 0.7391.

Conclusions:

  • Over one-third of 30-day mortality events after major amputation occur post-discharge.
  • The developed index effectively predicts 30-day mortality risk.
  • Patients with a score ≥5 require intensified postoperative management, including potential extended hospitalization or enhanced discharge follow-up.