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Updated: May 10, 2026

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice
Published on: June 15, 2020
Right ventricular loop indicating malposition of J-wire introducer for double lumen bicaval venovenous extracorporeal
Konstantin Yastrebov1, Con Manganas2, Tejo Kapalli3
1Department of Intensive Care Medicine, St. George Hospital, Conjoint Associate Professor UNSW, Australia.
Abstract:
The key to safe placement of a bicaval double lumen cannula for Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) is to visualise correct guide wire placement in the inferior vena cava (IVC), thus aiding subsequent correct advancement of the cannula. Transoesophageal (TOE) and transthoracic (TTE) echocardiography, as well as fluoroscopy, have been described as aiding imaging techniques. We report a case of guide wire malposition into the right ventricle, despite echocardiographic confirmation of guide wire position deep into the IVC. This malposition, if undetected, may have resulted in potential life threatening complications.
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