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Adverse drug reactions induced by valproic acid

Radu M Nanau1, Manuela G Neuman

  • 1Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, In Vitro Drug Safety and Biotechnology, Toronto, Ontario, Canada.

Clinical Biochemistry
|June 25, 2013
PubMed
Abstract

Keywords:
ADRAEDAHSALPALTASTAdverse drug reactionsAlpers-Huttenlocher syndromeCICYPDRESSDrug monitoringHHVHepatocytotoxicityIQMELASMitochondrial toxicityORPOLGSCARSJSStevens–Johnson syndromeTENVPAValproic acidadverse drug reactionalanine aminotransferasealkaline phosphataseantiepileptic drugaspartate aminotransferaseconfidence intervalcytochrome p450drug reaction with eosinophilia and systemic symptomshuman herpes virusintelligence quotientmitochondrial DNA polymerase γmitochondrial myopathy, encephalopathy, lactic acidosis and strokeodds ratiosevere cutaneous adverse reactiontoxic epidermal necrolysisvalproic acidγ-GTPγ-glutamyl transpeptidase

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