Related Experiment Video

Updated: May 10, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

A multicenter study of neurocognition in children with hypertension: methods, challenges, and solutions

Marc B Lande1, Heather R Adams, Juan C Kupferman

  • 1Department of Pediatrics, University of Rochester, Rochester, NY.

Journal of the American Society of Hypertension : JASH
|June 25, 2013
PubMed

Insights

Children with hypertension may show early signs of brain damage, impacting neurocognitive function. This multicenter study investigates these differences in pediatric hypertension to understand brain health.

Area of Science:

  • Pediatric Neurology
  • Cardiovascular Research
  • Neuroscience

Background:

  • Hypertension in adults is linked to reduced neurocognitive performance.
  • Preliminary evidence suggests similar neurocognitive differences in children with hypertension.
  • These differences may indicate early hypertensive target organ damage to the brain.

Purpose of the Study:

  • To investigate neurocognitive differences in children with primary hypertension.
  • To address limitations of previous single-center and database studies.
  • To outline the methods and challenges of a prospective, multicenter study in pediatric hypertension.

Main Methods:

  • Prospective, multicenter study design.
  • Focus on neurocognition in children with primary hypertension.
  • Detailed methodology addressing research challenges.

Main Results:

  • Study is ongoing; results not yet available in this methods-focused article.
  • Highlights unique challenges in pediatric hypertension neurocognition research.
  • Details study design solutions for these challenges.

Conclusions:

  • Further research is needed to confirm neurocognitive differences in pediatric hypertension.
  • Understanding these differences is crucial for early detection of brain changes.
  • This study aims to provide robust data on neurocognition in pediatric hypertension.

Keywords:
Executive functionblood pressurecognitionpediatric

More Related Videos

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol13:09

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol

Published on: April 1, 2018

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Longitudinal Studies01:26

Longitudinal Studies

Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...