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Published on: April 28, 2022
Effects of Lifetime History of Use of Problematic Alcohol on HIV Medication Adherence
Aman Sharma1, Ravinder Kaur Sachdeva2, Mahendra Kumar3
1Department of Internal Medicine, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India amansharma74@yahoo.com.
Background:
The effects of previous alcohol abuse on antiretroviral therapy (ART) adherence have been less studied.
Materials And Methodology:
Participants were randomized to a 3-month group intervention or an individual-enhanced standard-of-care condition and assessed over 6 months. Individual assessment at baseline, 3, and 6 months was done; interviews included lifetime history of problematic alcohol use.
Results:
A total of 80 HIV-positive individuals on ART were recruited. In all, 35% of participants reported a history of problematic alcohol use, 37% had a detectable viral load, 55% were nonadherent, and 24% reporting skipping medication in the previous 3 months. There was no association between a history of problematic use and an adherence at any time point, that is, at baseline (t = -.7, P = .47), midpoint (t = -.39, P = .69), and 6-month follow-up (t = -1.2, P = .23).
Conclusion:
Results suggest that a history of problematic alcohol use may not impact ART adherence.
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