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The NGS WikiBook: a dynamic collaborative online training effort with long-term sustainability
Jing-Woei Li1, Dan Bolser, Magnus Manske
1School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR. Tel.: +852-39431302; marcowanger@gmail.com.
Briefings in Bioinformatics
|June 25, 2013
Summary
Next-generation sequencing (NGS) generates vast data, requiring standardized bioinformatics protocols. The NGS WikiBook offers a collaborative, open-source platform for biologists to learn and share best practices in NGS data analysis.
Area of Science:
- Biomedical research
- Bioinformatics
- Genomics
Background:
- Next-generation sequencing (NGS) is fundamental to modern biomedical research.
- Increasing accessibility of NGS technology necessitates standardized bioinformatics protocols.
- Existing NGS informatics resources are fragmented and lack comprehensive synthesis.
Purpose of the Study:
- To address the fragmentation of NGS informatics resources.
- To create a centralized, collaborative platform for NGS data analysis best practices.
- To support bench biologists and non-bioinformaticians in navigating NGS data.
Main Methods:
- Initiation of a collaborative NGS resource using a Wikipedia framework (The NGS WikiBook).
- Development of a dynamic, online platform for content creation, editing, and searching.
- Inclusion of practical exercises for self-learning and skill development.
Main Results:
- A substantial amount of text has been collected to encourage community contribution.
- The NGS WikiBook provides a centralized synthesis of NGS informatics.
- The platform is designed for accessibility, allowing users to tailor their learning experience.
Conclusions:
- The NGS WikiBook serves as a collective laboratory book and protocol for NGS.
- It aims to establish community consensus on bioinformatics protocols for NGS data.
- Facilitates self-learning and community feedback in the rapidly evolving field of NGS.
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