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Published on: August 1, 2025
Tuberculous ascending aortic pseudoaneurysm
Syed Shahabuddin1, Shahid Ahmed Sami
1Cardiothoracic Surgery, The Aga Khan University Hospital, Karachi, Pakistan.
Abstract:
Pseudoaneurysms of the ascending aorta due to infective organisms are a rare but challenging entity with a risk of high morbidity and mortality. Previous cardiac surgery is an attributing factor, but they can present without previous surgical interventions. Various micro-organisms are responsible for this pathology. Tuberculous pseudoaneurysms of the ascending aorta are extremely rare. We report a case of a 25-year old man who presented to us with shortness of breath and recurrent haemoptysis. After preoperative evaluation including clinical and radiological assessment and echocardiography, he underwent successful repair of a pseudoaneurysm of the ascending aorta by excision and replacement of the diseased aorta with a Dacron tube graft using cardiopulmonary bypass. Postoperatively, he was started on antituberculous chemotherapy based on histological findings.
Insights
Tuberculous pseudoaneurysms of the ascending aorta are rare. This case highlights successful surgical repair and antituberculous chemotherapy for a young patient, improving outcomes for this challenging condition.
Area of Science:
- Cardiology
- Infectious Diseases
- Thoracic Surgery
Background:
- Infective pseudoaneurysms of the ascending aorta present a significant clinical challenge, associated with high morbidity and mortality.
- While previous cardiac surgery is a common risk factor, these aneurysms can also occur in patients without prior surgical history.
- Various microorganisms can cause these pseudoaneurysms, with tuberculous etiology being exceptionally rare.
Observation:
- A 25-year-old male presented with dyspnea and recurrent hemoptysis, indicative of a serious underlying cardiovascular and pulmonary issue.
- Preoperative assessments, including clinical evaluation, radiological imaging, and echocardiography, were crucial in diagnosing the ascending aortic pseudoaneurysm.
Findings:
- The patient underwent successful surgical repair of the ascending aortic pseudoaneurysm via excision and Dacron tube graft replacement under cardiopulmonary bypass.
- Histological examination confirmed the tuberculous nature of the pseudoaneurysm, guiding postoperative treatment.
Implications:
- This case underscores the importance of considering rare infectious etiologies, such as tuberculosis, in the differential diagnosis of ascending aortic pseudoaneurysms.
- Successful surgical management combined with targeted antituberculous chemotherapy offers a viable treatment strategy for this life-threatening condition.
- Early diagnosis and prompt intervention are critical for improving patient outcomes in cases of infective ascending aortic pseudoaneurysms.
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