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Peptic ulcer disease in children: an uncommon disorder with subtle symptomatology
Çiğdem Ömür Ecevıt1, Funda Özgenç, Hasan Ali Yüksekkaya
1Ege University, Department of Pediatric Gastroenterology, İzmir, Turkey.
Insights
Peptic ulcer disease is uncommon in children, often presenting with vague symptoms. Diagnosis relies on endoscopy, as symptoms don't reliably predict gastrointestinal bleeding in this age group.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Pathology
Background:
- Limited data exists on peptic and infectious ulcers in children.
- Understanding prevalence and symptoms is crucial for pediatric ulcer diagnosis.
Purpose of the Study:
- To investigate the prevalence of ulcers in children.
- To identify common presenting symptoms and their diagnostic significance.
- To evaluate the role of Helicobacter pylori in pediatric ulcers.
Main Methods:
- Retrospective analysis of upper gastrointestinal endoscopy charts from 2000-2009.
- Inclusion of all pediatric patients diagnosed with ulcers.
- Collection of demographic, clinical, endoscopic, and histopathologic data.
Main Results:
- Ulcer disease found in 3.4% of 902 pediatric patients.
- Common symptoms included abdominal pain (68%), hematemesis/melena (55%), and vomiting (39%).
- Helicobacter pylori identified in 61% of ulcer patients; symptoms did not differ significantly between H. pylori-positive and -negative groups.
Conclusions:
- Ulcer disease is infrequent in children and presents with nonspecific symptoms.
- Clinical symptoms are insufficient for diagnosing peptic ulcer disease before gastrointestinal bleeding in pediatric patients.
Background/Aims:
Data concerning peptic and infectious ulcers in children are limited. The aim of the study was to investigate the prevalence, presenting symptoms and significance of symptomatology in ulcer diagnosis in the pediatric age group.
Materials And Methods:
Between January 2000 and 2009, upper gastrointestinal endoscopy charts were examined retrospectively. All children in whom a diagnosis of ulcer was established were included in the study. Demographic, clinical, endoscopic, and histopathologic data were obtained from the patients' records. Peptic ulcer disease prevalence, presenting symptoms and symptomatology were evaluated.
Results:
Ulcer disease was observed in 31 (3.4%) of 902 patients. The mean age was 10.85 ± 4.25 (range: 2-17 years), and the male to female ratio was 2:1. The most common symptom was chronic abdominal pain (68%), hematemesis and melena (55%) and vomiting (39%). Helicobacter pylori was identified in 19 patients (61%) with ulcer. In the Helicobacter pylori-positive group, upper intestinal bleeding and pain were the major symptoms. Symptom frequency was not different between Helicobacter pylori-positive and -negative patients (p>0.05).
Conclusions:
Ulcer disease is an uncommon disorder in children with nonspecific clinical symptoms. Unlike the adult population, symptoms fail to diagnose peptic ulcer disease before gastrointestinal bleeding occurs.
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