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Updated: May 10, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Prognostic markers for acute heart failure.
Domingo A Pascual-Figal1, Luis Caballero, Jesús Sanchez-Mas
1University of Murcia, Virgen de la Arrixaca University Hospital and School of Medicine, Department of Cardiology, Murcia, Spain Ctra. Madrid-Cartagena s/n, 30120, Murcia, España. dpascual@um.es
Risk stratification for acute heart failure (AHF) uses clinical and biomarker data. Improved risk models are needed to guide patient management and reduce healthcare costs.
Area of Science:
- Cardiology
- Internal Medicine
- Geriatrics
Background:
- Acute heart failure (AHF) is a primary cause of hospitalization for individuals over 65.
- AHF presents a significant health burden due to high mortality, readmission rates, and healthcare costs.
Purpose of the Study:
- To review current individual markers for risk stratification in AHF.
- To analyze the complementary value, monitoring, and predictive capabilities of various risk markers.
Main Methods:
- Review of clinical, cardiorenal, hemodynamic, neurohormonal, and cardiac biomarkers.
- Analysis of risk models and event prediction strategies for AHF.
Main Results:
- Standard risk markers include congestion, perfusion, renal function, natriuretic peptides, and cardiac troponins.
- Current risk stratification relies on integrating bedside evaluation and laboratory biomarkers.
Conclusions:
- Despite established markers, research findings often fail to improve clinical management or reduce costs.
- Prospective research is essential to validate risk models in emergency settings for better patient stratification and therapeutic guidance.
- Identifying specific markers for recurrent AHF risk is crucial for clinical practice advancement.
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