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Updated: May 10, 2026

A Novel Application of Musculoskeletal Ultrasound Imaging
Published on: September 17, 2013
Molecular imaging: an innovative force in musculoskeletal radiology
Andrew Wilmot1, Simone Gieschler, Deepak Behera
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Objective:
A review of the innovative role molecular imaging plays in musculoskeletal radiology is provided. Musculoskeletal molecular imaging is under development in four key areas: imaging the activity of osteoblasts and osteoclasts, imaging of molecular and cellular biomarkers of arthritic joint destruction, cellular imaging of osteomyelitis, and imaging generators of musculoskeletal pain.
Conclusion:
Together, these applications suggest that next-generation musculoskeletal radiology will facilitate quantitative visualization of molecular and cellular biomarkers, an advancement that appeared futuristic just a decade ago.
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