Fetal thrombotic vasculopathy accompanied by fetal growth restriction

Fetal thrombotic vasculopathy, a rare condition, is defined as thrombosis in the fetal circulation of placenta causing fibrotic villi and its detection before delivery is difficult. Thrombosis in fetal placenta involves various problems such as uteroplacental insufficiency, central nervous system injury and even perinatal death. Here, we report a case of fetal arterial thrombosis predisposed to neonatal neurologic impairment. This case emphasizes an importance of placental biopsy, especially when the neonate seems to have problems. We recommend that pathological examination of placenta be performed not only when abnormal gross findings of placenta, but also when fetal abnormalities are observed.