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Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces
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Published on: September 26, 2014

Polyurethane adhesive ingestion.

Kevin T Fitzgerald1, Alvin C Bronstein

  • 1VCA Alameda East Veterinary Hospital, Denver, CO, USA. kfitzgerald@aevh.com

Topics in Companion Animal Medicine
|June 26, 2013
PubMed
Summary
This summary is machine-generated.

Ingesting polyurethane adhesives, like expanding wood glues containing diphenylmethane diisocyanate (MDI), can create dangerous gastrointestinal foreign bodies. Surgical removal is the safest and most effective treatment for these life-threatening blockages.

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Area of Science:

  • Veterinary Medicine
  • Toxicology
  • Gastroenterology

Background:

  • Polyurethane adhesives, common in households, pose a risk if ingested by pets.
  • Expanding wood glues containing diphenylmethane diisocyanate (MDI) can form significant gastrointestinal foreign bodies.
  • Public awareness of these risks is limited.

Purpose of the Study:

  • To describe the formation and consequences of gastrointestinal foreign bodies caused by polyurethane adhesive ingestion.
  • To evaluate diagnostic and therapeutic strategies for these ingestions.
  • To highlight the need for public education on this hazard.

Main Methods:

  • Review of clinical signs, diagnostic imaging (radiographs), and treatment outcomes.
  • Discussion of the pathophysiology of adhesive polymerization in the GI tract.
  • Evaluation of the efficacy of various interventions, including emesis, dilution, and endoscopy.

Main Results:

  • Ingested MDI-based glues polymerize rapidly, forming firm masses 4-8 times their original size.
  • Clinical signs appear within 12 hours and include anorexia, vomiting, and abdominal pain.
  • Complications include obstruction, perforation, and potentially death.
  • Radiographs can detect the "glue-ball" foreign body as early as 4-6 hours post-ingestion.
  • Emesis, dilution, and endoscopy are generally ineffective or contraindicated.
  • Surgical intervention is the most effective treatment, leading to recovery if performed early.

Conclusions:

  • Polyurethane adhesive ingestion is a serious veterinary emergency.
  • Early surgical intervention is crucial for successful outcomes.
  • Public education is essential to prevent accidental ingestion and promote pet safety.