Related Experiment Video
Updated: May 10, 2026
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Adrenal tumours in childhood]
G A Martos-Moreno1, J Pozo-Román, J Argente
1Servicios de Pediatría y Endocrinología, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, España.
Anales De Pediatria (Barcelona, Spain : 2003)
|June 26, 2013
Summary
This article reviews adrenal gland tumors, including adrenocortical tumors and catecholamine-secreting phaeochromocytomas (PCC) and paragangliomas (PG). It covers their genetics, diagnosis, and treatment strategies.
Area of Science:
- Endocrinology
- Oncology
- Genetics
Context:
- Adrenal gland tumors encompass adrenocortical tumors and neuroendocrine tumors like phaeochromocytomas and paragangliomas.
- These tumors originate from different adrenal tissues and can exhibit varying clinical behaviors.
Purpose:
- To provide a comprehensive overview of current knowledge on adrenal gland tumors.
- To detail the pathogenic and genetic underpinnings, clinical manifestations, diagnostic methods, and management strategies for these conditions.
Summary:
- Adrenocortical tumors arise from the adrenal cortex.
- Phæochromocytomas and paragangliomas are neuroendocrine tumors originating from neural crest cells, with phæochromocytomas specifically arising from the adrenal medulla.
- The review covers tumor genetics, clinical presentation, diagnostic modalities (biochemical, hormonal, imaging, molecular), and treatment (surgery, medical management, chemo- and radiotherapy).
Impact:
- Enhances understanding of adrenal gland tumor complexities.
- Informs clinical practice regarding diagnosis and management.
- Highlights current and emerging therapeutic approaches for improved patient outcomes.
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