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Characterization of a novel proinflammatory effect mediated by BK and the kinin B₂ receptor in human preadipocytes

Rose-Marie Catalioto1, Claudio Valenti, Luca Liverani

  • 1Pharmacology Department, Menarini Ricerche SpA, Via Rismondo 12A, 50131 Florence, Italy. chimfarm@menarini-ricerche.it

Biochemical Pharmacology
|June 26, 2013
PubMed

Keywords:
4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonateANGPTL-4Adipokines secretionAng-1Ang-2BrdUDAKDDALKDERK(1/2)FCSFasitibant chlorideGPDHHBSSHank's balanced salt solutionHuman preadipocytesIGFBP-2ILKinin B(2) receptorLDHLys-[Leu(8)][des-Arg(9)]-BKLys-[des-Arg(9)]-BKMCP-1MMPPGProinflammatory cytokinesSn-glycerol-3-phosphate dehydrogenaseTIMPWST-1[Ca(2+)]iangiopoietin-1angiopoietin-2angiopoietin-related protein 4bromodeoxyuridineextracellular signal-regulated kinases 1 and 2foetal calf seruminsulin-like growth factor binding protein-2interleukinintracellular calcium ion concentrationlactate dehydrogenasematrix metalloproteinasemonocyte chemoattractant protein-1prostaglandinsTNFRIsTNFRIIsoluble tumor necrosis factor receptor type Isoluble tumor necrosis factor receptor type IItissue inhibitor of metalloproteinasesbradykinin signalingpreadipocyte inflammationkinin B2 receptoradipokine secretion

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