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Updated: May 10, 2026
08:13
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Left ventricular basal region involvement in noncompaction cardiomyopathy.
Marcelo Dantas Tavares de Melo1, Luiz A Benvenuti, Charles Mady
1Heart Institute (InCor) da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Summary
Noncompaction cardiomyopathy (NCC) involves prominent ventricular trabeculations. This case highlights diagnostic challenges and the need to correlate trabeculation volume with prognosis in patients with this rare heart condition.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Pathology
Background:
- Noncompaction cardiomyopathy (NCC) is a rare congenital heart disease characterized by prominent ventricular trabeculations.
- Diagnostic criteria for NCC lack universal consensus, posing challenges in clinical practice.
Observation:
- A previously healthy 16-year-old female presented with progressive dyspnea on exertion.
- Echocardiography and cardiac MRI revealed dilated cardiac chambers, severe biventricular systolic dysfunction, and marked ventricular hypertrabeculation, indicative of NCC.
Findings:
- The patient underwent heart transplantation 5 years post-NCC diagnosis.
- Post-transplant pathological examination confirmed diffuse biventricular hypertrabeculation, affecting even the basal walls.
Implications:
- This case underscores the need for a conceptual review of diagnostic criteria for noncompaction cardiomyopathy.
- Further research is warranted to establish the relationship between trabeculation volume and patient prognosis in NCC.
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