Related Experiment Video
Updated: May 10, 2026
07:51
Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
Gout: a critical analysis of scientific development
Rheumatology International
|June 26, 2013
Summary
This scientometric analysis of gout research from 1990-2012 reveals publication trends and identifies key contributors. It highlights the need for critical evaluation of scientometric indicators in gout research.
Area of Science:
- Rheumatology
- Gout Research
- Scientometrics
Background:
- Scientific focus on gout pathogenesis has advanced anti-inflammatory and urate-lowering therapies.
- A scientometric analysis of gout research is needed due to evolving academic evaluation and citation practices.
Purpose of the Study:
- To evaluate the quality and quantity of scientific research on gout.
- To identify key publications, authors, institutions, and collaborations in gout research.
- To provide a basis for distinguishing relevant research output in the field.
Main Methods:
- Utilized scientometric methods and large-scale data analysis.
- Collected data from PubMed and ISI-Web databases.
- Analyzed publications from 1990 to 2012.
Main Results:
- 4,424 publications were identified from 71 countries over 22 years.
- The USA was the most productive country (32%), followed by the UK, Japan, Spain, and Germany.
- Key journals included 'Arthritis and Rheumatism,' 'Annals of the Rheumatic Diseases,' and 'Journal of Rheumatology.'
Conclusions:
- The USA leads in gout research output and international collaboration.
- Specific journals, authors, and institutions are identified as major contributors to gout literature.
- Scientometric indicators like h-index and impact factor require critical assessment due to potential biases from self-citation and co-authorship.
Related Concept Videos
01:11Genome-wide Association Studies-GWAS
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
01:32The Scientific Method
The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
02:58Regulated Protein Degradation
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
01:26Gastritis II: Pathophysiology
The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...