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Screening for hepatitis C virus infection in adults: U.S. Preventive Services Task Force recommendation statement
Annals of Internal Medicine
|June 26, 2013
Summary
The U.S. Preventive Services Task Force (USPSTF) recommends hepatitis C virus (HCV) screening for high-risk adults and all adults born between 1945-1965. This update provides current evidence for HCV screening and treatment in asymptomatic individuals.
Area of Science:
- Public Health
- Preventive Medicine
- Infectious Diseases
Background:
- The U.S. Preventive Services Task Force (USPSTF) previously issued recommendations on hepatitis C virus (HCV) screening and treatment in 2004.
- Evidence gaps identified in the 2004 recommendation and new research necessitated an update.
Purpose of the Study:
- To provide an updated recommendation on screening for and treatment of HCV infection in asymptomatic adults.
- To review new evidence on HCV screening and treatment, including in pregnant women.
Main Methods:
- Commissioned two systematic reviews to evaluate evidence on HCV screening and treatment in asymptomatic adults.
- Considered new studies published since 2004 and evidence regarding screening in pregnant women.
Main Results:
- The USPSTF recommends screening for HCV infection in individuals at high risk.
- A "B" recommendation was issued for offering one-time HCV screening to adults born between 1945 and 1965.
Conclusions:
- Routine screening for HCV infection is recommended for adults born between 1945 and 1965.
- Screening is also recommended for individuals identified as high risk for HCV infection.