Impact of concomitant coronary artery bypass grafting on in-hospital outcome in octogenarians undergoing aortic valve replacement
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Updated: May 10, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Shahzad G Raja1, Manoraj Navaratnarajah, Mubassher Husain
1Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom. drrajashahzad@hotmail.com
Insights
In octogenarians, combined aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) show similar in-hospital outcomes to isolated AVR. This supports the combined procedure in carefully selected elderly patients.
Area of Science:
- Cardiovascular Surgery
- Geriatric Cardiology
- Cardiac Surgery Outcomes
Background:
- Surgical aortic valve replacement (AVR) in octogenarians has excellent in-hospital outcomes.
- Limited data exists on concomitant AVR and coronary artery bypass grafting (CABG) outcomes in this age group.
- This study compares in-hospital outcomes of combined AVR and CABG versus isolated AVR in octogenarians.
Purpose of the Study:
- To compare the in-hospital outcomes of concomitant AVR and CABG versus isolated AVR in octogenarians.
- To evaluate the safety and efficacy of combined cardiac procedures in elderly patients.
- To provide evidence for decision-making in high-risk cardiac surgery patients.
Main Methods:
- Retrospective analysis of a prospectively collected cardiac surgery database.
- Comparison of 114 octogenarians undergoing AVR + CABG with 68 octogenarians undergoing isolated AVR.
- Review of medical notes and charts for detailed outcome assessment.
Main Results:
- Both groups had similar mean age, demographics, and EuroSCORE.
- Longer aortic cross-clamp and cardiopulmonary bypass times were observed in the AVR + CABG group.
- In-hospital mortality was comparable (7.4% vs. 9.6%), with a higher need for hemofiltration in the AVR + CABG group.
Conclusions:
- Concomitant AVR and CABG in octogenarians yield in-hospital outcomes comparable to isolated AVR.
- The combined procedure is justified in carefully selected high-risk elderly patients.
- This finding supports the consideration of combined AVR and CABG for eligible octogenarians.
Background And Aim Of The Study:
Abundant data are available reporting excellent in-hospital outcomes after surgical aortic valve replacement (AVR) in octogenarians. However, there is a paucity of studies reporting the in-hospital outcome of concomitant AVR and coronary artery bypass grafting (CABG) in this group of patients. Hence, a comparison was made of the impact of concomitant AVR and CABG versus isolated AVR on in-hospital outcome in octogenarians.
Methods:
Between January 2001 and October 2011, a total of 114 consecutive octogenarians undergoing combined AVR and CABG were compared with a control group of octogenarians (n = 68) undergoing isolated AVR. A retrospective analysis was performed of a prospectively collected cardiac surgery database. In addition, the medical notes and charts of all study patients were reviewed.
Results:
The two groups had a similar mean age (AVR 82.3 +/- 2.4 years versus AVR + CABG 82.6 +/- 2.1 years; p = 0.91), demographics and EuroSCORE (AVR 11.4 versus AVR + CABG 13.2; p = 0.12). The aortic cross-clamp and cardiopulmonary bypass times were longer for AVR + CABG patients (p < 0.001). In-hospital mortality (7.4% after isolated AVR, 9.6% after AVR + CABG; p = 0.35 between groups) and major clinical outcomes for the two groups were found to be similar except for an increased need for hemofiltration in AVR + CABG patients (p = 0.02).
Conclusion:
In-hospital outcomes for concomitant AVR and CABG in octogenarians are comparable to those of isolated AVR, justifying the performance of combined AVR and CABG in this high-risk group of carefully selected patients.
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