Related Experiment Video
Updated: May 10, 2026

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
Quality of life in symptomatic HIV infected children
Mohit Gupta1, Sanjiv Nanda, Jaya Shankar Kaushik
1Department of Pediatrics, Pt B D Sharma Postgraduate Insititute of Medical Sciences, Rohtak, Haryana, India. Correspondence to: Dr Sanjiv Nanda, Professor, Department of Pediatrics, PT B D Sharma Postgraduate Institute of Medical Sciences, Rohtak 124 001, Haryana, India. drsanjivnanda@gmail.com.
Insights
Quality of life in children with HIV in North India was better than in those with other chronic illnesses. HIV-infected children showed improved psychosocial, emotional, and school functioning compared to controls.
Area of Science:
- Pediatrics
- Infectious Diseases
- Quality of Life Research
Background:
- Childhood chronic illnesses significantly impact quality of life.
- Human Immunodeficiency Virus (HIV) infection presents unique challenges for affected children.
- Understanding quality of life (QOL) in pediatric HIV is crucial for comprehensive care.
Purpose of the Study:
- To compare the quality of life (QOL) between children infected with HIV and demographically matched controls with other chronic ailments.
- To identify factors influencing QOL in pediatric HIV cases.
Main Methods:
- A case-control study was conducted with 40 children with HIV and 40 controls with other chronic conditions.
- Participants were recruited from a referral hospital in Northern India.
- Quality of life was assessed using standardized measures, comparing scores between groups.
Main Results:
- HIV-infected children demonstrated significantly better QOL in psychosocial (P=0.008), emotional (P=0.001), and school functioning (P=0.039) domains.
- Age, gender, socioeconomic status, and clinical/immunological staging of HIV did not significantly affect QOL scores.
- Overall QOL in HIV-infected children was superior to that of children with other chronic illnesses.
Conclusions:
- Quality of life in children with HIV in North India is notably better than in those with other chronic childhood diseases.
- Psychosocial, emotional, and school functioning are key areas where HIV-infected children may experience advantages.
- Further research can explore interventions to maintain and enhance QOL in pediatric HIV.
Abstract:
We conducted a case control study to compare the quality of life (QOL) in 40 cases of HIV infected children and 40 demographically matched controls with other chronic ailments at a referral hospital in Northern India. Quality of life among HIV infected children was significantly better in psychosocial (P=0.008), emotional (P=0.001) and school (P=0.039) functioning. Factors including age (P=0.07), gender (P=0.44), socioeconomic status (P=0.99), clinical (P=0.18) and immunological staging (P=-0.91) of HIV infection did not significantly influence QOL scores. Hence, quality of life in HIV infected children of North India was better than those suffering from other childhood chronic illness.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Retrovirus Life Cycles
Sexually Transmitted Infections
