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Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Nitric oxide modulators: an emerging class of medicinal agents
S R Deshpande1, K Satyanarayana, M N A Rao
1Department of Medicinal and Pharmaceutical Chemistry, HSK College of Pharmacy, Bagalkote-587 101, India.
Indian Journal of Pharmaceutical Sciences
|June 27, 2013
Summary
Nitric oxide (NO) is a vital messenger molecule involved in numerous bodily functions. Modulating NO levels through donors or inhibitors may offer new therapeutic strategies for various diseases.
Area of Science:
- Biochemistry
- Physiology
- Pharmacology
Background:
- Nitric oxide (NO) acts as a crucial signaling molecule in virtually all tissues.
- NO plays diverse roles in physiological processes, including vascular tone, platelet aggregation, neurotransmission, and immune responses.
Purpose of the Study:
- To review the biological chemistry of nitric oxide modulators.
- To explore the potential of NO modulation for novel clinical strategies.
Main Methods:
- Literature review of nitric oxide modulators.
- Analysis of scientific advancements in NO research.
Main Results:
- Nitric oxide is involved in a wide array of essential biological functions.
- Modulation of NO synthesis or release presents promising therapeutic avenues.
Conclusions:
- Understanding NO modulators is key to developing new treatments.
- Targeting nitric oxide pathways offers a fruitful area for future medical research.
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