Is there any difference between non-obese male and female in response to cardiac rehabilitation programs?

Masoumeh Sadeghi1, Fatemeh E Ghashghaei, Katayoun Rabiei

  • 1Cardiac Rehabilitation Research Center, Isfahan Cardiovascular, Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Insights

A supervised cardiac rehabilitation program significantly improved functional capacity and lipid profiles in non-obese males and females with coronary artery disease. The program showed benefits for both genders, with notable improvements in functional capacity between groups.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Exercise Physiology

Background:

  • Coronary artery disease (CAD) is a leading global cause of mortality and morbidity.
  • Sedentary lifestyles and dyslipidemia are key risk factors for CAD progression.
  • Gender-specific differences exist in CAD risk between non-obese males and females.

Purpose of the Study:

  • To evaluate the impact of a comprehensive cardiac rehabilitation program (CRP) on functional capacity and lipid profiles.
  • To compare the benefits of CRP between non-obese males and females with CAD.
  • To assess changes in total cholesterol, triglycerides, LDL-C, and HDL-C.

Main Methods:

  • 585 non-obese male and female CAD patients participated in a 2-month CRP.
  • The program included 24 supervised exercise sessions, medical evaluations, and consultations.
  • Functional capacity and lipid profiles were assessed via exercise tests and blood samples pre- and post-program.

Main Results:

  • Significant improvements in functional capacity (P=0.00) and most lipid profiles were observed in both groups.
  • High-density lipoprotein cholesterol (HDL-C) did not significantly improve in non-obese females.
  • While lipid profiles showed no significant gender differences, functional capacity changes were significant between groups (P=0.00).

Conclusions:

  • Supervised CRP is crucial for enhancing functional capacity and lipid profiles in non-obese CAD patients.
  • The program demonstrates effectiveness irrespective of gender.
  • Improvements in functional capacity were notably significant between male and female participants.
Abstract

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