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Published on: September 22, 2017
Cardiopulmonary bypass in an infant with a recent history of malaria
Hamish M Munro1, Monica C Olsen, Cathy L Smith
1The Heart Center, Arnold Palmer Hospital for Children, Orlando, FL 32806, USA. hamish.munro@orlandohealth.com
Insights
Severe malaria can harm heart function. This case study details a child with impaired left ventricular function after tetralogy of Fallot repair post-malaria treatment, highlighting potential cardiac complications.
Area of Science:
- Cardiology
- Infectious Diseases
- Pediatrics
Background:
- Severe malaria is linked to cardiac dysfunction.
- Tetralogy of Fallot is a congenital heart defect requiring surgical repair.
- Cardiopulmonary bypass (CPB) is a standard procedure in cardiac surgery.
Observation:
- A pediatric patient underwent tetralogy of Fallot repair two weeks after malaria treatment.
- The patient experienced impaired left ventricular function post-surgery.
Findings:
- The case suggests a potential link between recent severe malaria and postoperative cardiac complications, specifically impaired left ventricular function.
- Malaria's impact on cardiac function, particularly in the context of congenital heart disease surgery, warrants further investigation.
Implications:
- This case highlights the importance of considering recent severe infections, like malaria, when assessing cardiac risk in pediatric patients undergoing surgery.
- Understanding malaria's pathophysiology is crucial for managing potential cardiac complications in affected children.
- Further research is needed to elucidate the mechanisms by which malaria affects cardiac function and its implications for surgical outcomes.
Abstract:
Severe malarial infection is associated with impaired cardiac function. We report a child who underwent repair of tetralogy of Fallot two weeks after being treated for malaria. The postoperative course was complicated by impaired left ventricular function. The pathogenesis of malaria is discussed as well as the potential complications of cardiopulmonary bypass (CPB).

