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Updated: May 10, 2026

Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
Published on: June 9, 2023
Greater effect of adiposity than physical activity or lean mass on physical function in community-dwelling older
Christie L Ward1, Rudy J Valentine, Ellen M Evans
1Dept. of Kinesiology, University of Georgia, Athens, GA.
Abstract:
Adiposity, lean mass, and physical activity (PA) are known to influence physical function in older adults, although the independent influences are not completely characterized. Older adults (N = 156, M age = 68.9 ± 6.7 yr, 85 men) were assessed for body composition via dual-energy X-ray absorptiometry, PA by accelerometer, and physical function via timed up-and-go (UP&GO), 30-s chair stand, 6-min walk (6-min WALK), and Star-Excursion Balance Test. In the absence of percentage-body-fat by PA interactions (p > .05), main effects existed such that a higher percentage body fat was associated with poorer performance in UP&GO, 30-s chair stand, and 6-min WALK (p < .05). No significant main effects were found for PA and functional performance. Adiposity explains 4.6-11.4% in physical functional variance (p < .05). Preventing increases in adiposity with age may help older adults maintain functional independence.
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