Related Experiment Video
Updated: May 10, 2026
A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
Published on: March 8, 2017
Autoimmune inner ear disease preliminary case report: audiometric findings following steroid treatments
Dave A Harris1, Anthony A Mikulec, Sarah L Carls
1Saint Louis University School of Medicine, MO, USA.
Purpose:
This study examined the audiometric findings following steroid treatment for autoimmune inner ear disease (AIED), which is characterized by bilateral subacute hearing loss, using oral and intratympanic treatment.
Method:
The charts of 9 patients with AIED who had been seen in the Saint Louis University School of Medicine's clinic between 2004 and 2011 were reviewed, with special focus on audiometric results.
Results:
The majority of patients benefited from treatment for AIED. Four patients (6 ears) received intratympanic therapy as part of their treatment.
Conclusion:
Patients with AIED appeared to benefit from a clinical pathway using a prolonged course of oral steroids, followed by a trial of intratympanic steroids and/or immunosuppresants for refractory cases.
