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Published on: June 24, 2018
In vitro anti-caries effect of fluoridated hydroxyapatite-coated preformed metal crowns
D R Clark1, A Czajka-Jakubowska, C Rick
1Department of Cariology, Restorative Sciences, and Endodontics, School of Dentistry, Room 2391, University of Michigan , 1011 N University Ave, Ann Arbor, MI, 48109-1078, USA.
Summary
Fluoridated hydroxyapatite (FA) crystals synthesized on preformed metal crowns (PMCs) release fluoride and prevent cavities. FA-coated PMCs offer an aesthetic, inexpensive, and caries-preventive dental solution.
Area of Science:
- Biomaterials Science
- Cariology
- Dental Materials
Background:
- Dental caries remains a significant global health issue.
- Preformed metal crowns (PMCs) are widely used in pediatric dentistry.
- Caries development at the crown-tooth interface is a clinical concern.
Purpose of the Study:
- To synthesize fluoridated hydroxyapatite (FA) crystals directly onto PMCs.
- To evaluate the anti-cariogenic properties of FA-coated PMCs in an in vitro model.
Main Methods:
- FA crystals were grown on etched PMCs and stainless steel discs.
- Fluoride release was measured from FA-coated discs at varying pH levels.
- FA-coated and non-coated PMCs were cemented onto human molars and subjected to an acidic challenge for 9 weeks.
Main Results:
- Scanning Electron Microscopy (SEM) confirmed FA crystal growth on PMCs.
- FA-coated discs exhibited fluoride release (0.16 mg/L/cm² at pH < 5.0).
- Teeth with FA-coated PMCs showed significantly smaller carious lesions compared to controls.
Conclusions:
- FA-coated PMCs demonstrate effective fluoride release and reduce demineralization at the crown-tooth interface.
- FA-coated PMCs present a promising aesthetic, inexpensive, and caries-preventive alternative for clinical use.
