Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Convergent Evolution01:54

Convergent Evolution

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
Restriction Enzymes01:11

Restriction Enzymes

Restriction enzymes are bacterial enzymes used to cut DNA in a sequence-specific manner. To cleave DNA, they bind to specific palindromic sequences called restriction sites. Such palindromic DNA sequences or inverted repeats are commonly found in regions of functional significance, such as the origin of replication, gene operator sites, and regions containing transcription termination signals.
The host bacteria protect their own genomic DNA from these enzymes by methylating these sites. Some...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of Postoperative Efficacy and Safety of Celecoxib in Children Hospitalized After Adenotonsillectomy.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2024
Same author

Occlusal Outcomes in Non-Robin Sequence Patients with Isolated Cleft Palate.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association·2024
Same author

Navigation and non-navigation CT scan of the sinuses: comparison of the effective doses of radiation in children and adults.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale·2021
Same author

A Chart Audit Study of Clozapine Utilization in Early Psychosis.

Journal of clinical psychopharmacology·2021
Same author

Furlow Palatoplasty: Should We Also Focus on the Size of the Nasopharynx?

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association·2021
Same author

Necrotizing epiglottitis with necrotizing fasciitis in a child: A case report and review of literature.

International journal of pediatric otorhinolaryngology·2020

Related Experiment Video

Updated: May 10, 2026

Method of Studying Palatal Fusion using Static Organ Culture
04:58

Method of Studying Palatal Fusion using Static Organ Culture

Published on: September 19, 2015

Isolated versus pierre robin sequence cleft palates: are they different?

Audrey Godbout, Jacques E Leclerc, Isabelle Arteau-Gauthier

    The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
    |June 28, 2013
    PubMed
    Summary

    Patients with Pierre Robin (PR) sequence have significantly different cleft palate sizes compared to isolated clefts. Wider soft palate width in severe PR cases correlates with feeding and airway issues.

    Keywords:
    Pierre Robin sequencecleft palatepalatoplasty

    More Related Videos

    Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes
    07:13

    Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes

    Published on: February 13, 2021

    Isolation and Characterization of Satellite Cells from Rat Head Branchiomeric Muscles
    07:37

    Isolation and Characterization of Satellite Cells from Rat Head Branchiomeric Muscles

    Published on: July 20, 2015

    Related Experiment Videos

    Last Updated: May 10, 2026

    Method of Studying Palatal Fusion using Static Organ Culture
    04:58

    Method of Studying Palatal Fusion using Static Organ Culture

    Published on: September 19, 2015

    Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes
    07:13

    Isolation and Time-Lapse Imaging of Primary Mouse Embryonic Palatal Mesenchyme Cells to Analyze Collective Movement Attributes

    Published on: February 13, 2021

    Isolation and Characterization of Satellite Cells from Rat Head Branchiomeric Muscles
    07:37

    Isolation and Characterization of Satellite Cells from Rat Head Branchiomeric Muscles

    Published on: July 20, 2015

    Area of Science:

    • Craniofacial anomalies
    • Pediatric surgery
    • Genetics

    Background:

    • Cleft palate (CP) is a common congenital anomaly.
    • Pierre Robin (PR) sequence is characterized by micrognathia, glossoptosis, and airway obstruction, often associated with CP.
    • Understanding anatomical differences is crucial for surgical planning and patient outcomes.

    Purpose of the Study:

    • To compare the anatomical dimensions of isolated cleft palates (CPs) with those associated with Pierre Robin (PR) sequence.
    • To identify specific cleft characteristics that may correlate with clinical severity in PR sequence.

    Main Methods:

    • Prospective case series conducted at a tertiary care hospital from 1993 to 2011.
    • Patients with nonsyndromic isolated CP and PR sequence were classified as mild or severe based on respiratory/feeding difficulties.
    • Seven anatomical cleft parameters were measured during palatoplasty under general anesthesia.

    Main Results:

    • Fifty-seven isolated CP cases and 36 PR sequence cases were analyzed.
    • Severe PR cases showed a statistically significant larger soft palate width compared to isolated CP and mild PR.
    • Isolated clefts were significantly shorter in length and narrower in hard palate width compared to both mild and severe PR cases.

    Conclusions:

    • Cleft palates associated with PR sequence exhibit distinct anatomical features compared to isolated clefts.
    • Increased soft palate width in PR sequence is significantly correlated with increased airway and feeding problems, indicating greater clinical severity.