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Risk factor burden predicts long-term mortality after cerebral infarction

G Gjerde1, H Naess

  • 1Department of Neurology, Haukeland University Hospital, Bergen, Norway.

Acta Neurologica Scandinavica
|June 28, 2013
PubMed

Insights

The number of traditional risk factors significantly impacts long-term mortality after cerebral infarction. Patients with more risk factors face a higher risk of death, underscoring the need for careful monitoring.

Area of Science:

  • Cardiovascular Research
  • Neurology
  • Public Health

Background:

  • Previous research indicates a link between traditional risk factors and mortality in young stroke patients.
  • The cumulative effect of multiple risk factors on long-term outcomes requires further investigation.

Purpose of the Study:

  • To examine the association between the number of traditional risk factors and long-term mortality following cerebral infarction.
  • To determine if this association is independent of patient age.

Main Methods:

  • A cohort of acute cerebral infarction patients, alive 30 days post-stroke, was studied.
  • Traditional risk factors (hypertension, diabetes, smoking, etc.) were assessed.
  • Cox regression analyses were used to evaluate mortality risk over a mean follow-up of 2.4 years.

Main Results:

  • Mortality rates increased with the number of risk factors: 14% (none), 13% (1-3), 19% (4-5), and 26% (6+).
  • Each additional risk factor was associated with a 30% increased mortality risk (Hazard Ratio = 1.3).

Conclusions:

  • An increasing number of traditional risk factors is significantly associated with long-term mortality in cerebral infarction patients, regardless of age.
  • Close long-term follow-up is crucial for patients with multiple risk factors to mitigate mortality risk.
Abstract

Keywords:
cerebral infarctionlong-term mortalitytraditional risk factors

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