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Related Concept Videos

Pneumothorax II: Pathophysiology01:08

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...

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Extralobar pulmonary sequestration in a 55-year-old man.

Hai-yang Xuan1, Kai-hu Shi, Wen-hui Gong

  • 1Department of Cardiovascular Surgery, the Second Hospital of AnHui Medical University, Anhui, China.

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
|June 28, 2013
PubMed
Summary

Extralobar pulmonary sequestration, a rare congenital lung defect, can occur in adults. Three-dimensional computed tomography angiography (3D CTA) is crucial for diagnosing this condition by visualizing abnormal blood supply.

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Area of Science:

  • Pulmonology
  • Radiology
  • Congenital Malformations

Background:

  • Pulmonary sequestration is a rare congenital lung malformation.
  • Extralobar sequestration is more common in the left lung, typically near the lower mediastinum.
  • Adult presentation of extralobar sequestration is uncommon.

Observation:

  • A 55-year-old man presented with recurrent fever and cough.
  • Diagnosis was confirmed via three-dimensional computed tomography angiography (3D CTA).
  • 3D CTA revealed an abnormal vessel supplying the consolidated lung from the aortic arch.

Findings:

  • The patient underwent successful resection of the left pulmonary sequestration.
  • Postoperative pathological examination confirmed the diagnosis.
  • 3D CTA proved decisive in identifying the aberrant vasculature.

Implications:

  • This case highlights the importance of considering extralobar sequestration in adult patients with persistent respiratory symptoms.
  • 3D CTA is an invaluable tool for surgical planning in pulmonary sequestration.
  • Advanced imaging aids in the definitive diagnosis and management of rare congenital lung anomalies.