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Related Concept Videos

The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...

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Related Experiment Video

Updated: May 10, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

[Oral ecosystem in elderly people].

Marie-Hélène Lacoste-Ferré1, Sophie Hermabessière, Fabienne Jézéquel

  • 1CHU Toulouse Purpan, Hôpital Garonne, Toulouse. lacoste.mh@chu-toulouse.fr

Geriatrie Et Psychologie Neuropsychiatrie Du Vieillissement
|June 28, 2013
PubMed
Summary

Maintaining the oral ecosystem is crucial for elderly health, preventing malnutrition and oral diseases. Proper oral care strategies protect the delicate balance of the mouth in older adults.

Keywords:
gerodontologyoral acidityoral ecosystemoral microflorasalivary flow

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Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers
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Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers

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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
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Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

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Last Updated: May 10, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers
08:25

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers

Published on: December 18, 2013

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

Area of Science:

  • Oral biology and health
  • Geriatric medicine
  • Microbiology

Context:

  • The mouth is a vital digestive and communication organ, maintained by a balance between bacteria and saliva.
  • The oral ecosystem protects against pathologies like caries and periodontitis.
  • Aging impacts salivary flow, increases oral disease risk, and can destabilize this ecosystem.

Purpose:

  • To describe the oral physiopathology in the elderly, focusing on microflora and salivary secretion.
  • To outline strategies for preserving the oral ecosystem's balance in geriatric populations.
  • To highlight the importance of oral health for nutrition and overall well-being in older adults.

Summary:

  • Aging disrupts the oral ecosystem through reduced salivary flow, increased disease susceptibility, and external factors like dentures and systemic conditions.
  • This destabilization promotes dental plaque and weakens oral tissues, increasing risks of undernutrition.
  • Understanding oral microflora and salivary dynamics is key to developing protective strategies.

Impact:

  • Preserving the oral ecosystem ensures adequate nutrition for the elderly by enabling proper eating.
  • Proactive management of the oral environment can prevent common geriatric oral health issues.
  • This research supports improved quality of life for seniors through better oral health maintenance.