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Related Experiment Videos

Spontaneous peritonitis caused by Enterococcus faecium.

J Pascual1, A Sureda, A Lopez-San Roman

  • 1Department of Gastroenterology, Hospital Ramon y Cajal, Madrid, Spain.

Journal of Clinical Microbiology
|June 1, 1990
PubMed
Summary
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Enterococcus faecium, a bacterium not previously linked to spontaneous bacterial peritonitis, caused the condition in three patients with alcoholic cirrhosis. Two patients successfully responded to treatment, highlighting a new clinical consideration.

Area of Science:

  • Infectious Diseases
  • Hepatology
  • Microbiology

Background:

  • Spontaneous bacterial peritonitis (SBP) is a serious infection in patients with cirrhosis.
  • Commonly, SBP is caused by gram-negative bacteria, with Enterococcus species rarely implicated.
  • Alcoholic cirrhosis is a significant risk factor for SBP.

Observation:

  • Three cases of spontaneous peritonitis caused by Enterococcus faecium were identified.
  • All patients had underlying alcoholic cirrhosis.
  • This represents the first reported instances of Enterococcus faecium causing SBP.

Findings:

  • Two of the three patients with Enterococcus faecium peritonitis responded to antibiotic therapy.
  • The study reviews the development of enterococcal peritonitis and existing literature.

Related Experiment Videos

  • Taxonomic challenges associated with Enterococcus faecium are discussed.
  • Implications:

    • Enterococcus faecium should be considered in the differential diagnosis of SBP, particularly in patients with alcoholic cirrhosis.
    • Understanding the pathogen's role may refine diagnostic and therapeutic strategies for SBP.
    • Further research into the pathogenicity and treatment of enterococcal SBP is warranted.