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Related Experiment Video

Updated: May 10, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Do weight loss and adherence cluster within behavioral treatment groups?

Rena R Wing¹, Tricia Leahey, Robert Jeffery

¹The Miriam Hospital/Alpert Medical School, Providence, Rhode Island, 02903, USA.

Obesity (Silver Spring, Md.)

|June 28, 2013

Summary

Weight loss did not cluster in groups, but adherence measures did. Group characteristics like size or homogeneity did not impact weight loss outcomes in this intensive lifestyle intervention study.

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Area of Science:

Behavioral science
Public health
Clinical nutrition

Background:

Group-based weight loss programs are common for overweight/obese individuals with type 2 diabetes.
The impact of group dynamics and participant characteristics on weight loss outcomes is not well understood.

Purpose of the Study:

To investigate whether weight loss and adherence cluster within treatment groups.
To determine if group characteristics (size, homogeneity) influence weight loss outcomes in an intensive lifestyle intervention (ILI).

Main Methods:

Analysis of weight loss and adherence data (attendance, meal replacements, activity) over one year.
Examined 2329 ILI participants across 209 treatment groups in the multicenter Look AHEAD study.

Main Results:

Weight loss did not show significant clustering within groups (ICC=0.007).
Adherence measures exhibited small to moderate clustering (ICCs=0.05-0.11).
Neither group size nor baseline homogeneity affected weight loss outcomes, despite variations in group weight loss percentages.

Conclusions:

Controlling for clustering may not be essential in behavioral weight loss studies.
Group treatment alone is insufficient to leverage social influences for enhanced weight loss.