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Published on: January 16, 2026
Pediatric Ventricular Assist Devices: The Future (as of 2011)
Robert D B Jaquiss1, Andrew J Lodge
1Section of Pediatric Cardiothoracic Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Insights
Recent advancements in pediatric mechanical circulatory support offer new hope for children needing transplants. These devices aim to improve outcomes and reduce waiting list deaths for young patients.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Transplant Surgery
Background:
- Historically, extracorporeal membrane oxygenation was the primary option for pediatric mechanical circulatory support.
- Limited options previously existed for small children requiring bridge to transplant or recovery.
Purpose of the Study:
- To highlight recent advancements in pediatric mechanical circulatory support devices.
- To discuss the potential impact of new devices on transplant waiting list mortality and outcomes.
Main Methods:
- Review of recent developments in pediatric mechanical circulatory support technology.
- Analysis of industry and National Institutes of Health (NIH) driven innovations.
Main Results:
- Several new devices are in development for pediatric mechanical circulatory support.
- These devices promise improved quality of support for younger children.
- Potential exists to significantly reduce transplant waiting list mortality.
Conclusions:
- Significant progress has been made in pediatric mechanical circulatory support over the last decade.
- New devices offer improved options for pediatric patients awaiting transplantation or recovery.
- Increased funding, including from the NIH, is driving innovation in this field.
Abstract:
In the last decade, there have been enormous advances in the field of pediatric-specific mechanical circulatory support. In the past, small children requiring bridge to transplant or recovery were limited to extracorporeal membrane oxygenation. Now, in various stages of development, there are several devices that offer the promise of the same quality of support enjoyed by older teenagers and adolescents, with the potential to substantially reduce transplant waiting list mortality and optimize transplant outcomes. Advances have been driven by both industry and, for the first time, by funding from the US National Institutes of Health.
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