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Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers

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Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...

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A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure

A Pulmonary Trunk Banding Model of Pressure Overload Induced Right Ventricular Hypertrophy and Failure

Published on: November 29, 2018

Bilateral pulmonary artery banding

Andrea Quarti¹, Massimo Colaneri, Alessandra Baldinelli

¹Department of Congenital and Paediatric Cardiac Surgery and Cardiology, Azienda Ospedaliera, Ospedali Riuniti, Ancona, Italy.

World Journal for Pediatric & Congenital Heart Surgery

|June 28, 2013

Summary

No abstract available in PubMed .

Keywords:

hypoplastic left heart syndrome palliation pulmonary arteries stents

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