Related Experiment Video
Updated: May 10, 2026

Left Atrial Ligation in the Avian Embryo as a Model for Altered Hemodynamic Loading During Early Vascular Development
Published on: June 16, 2023
Hematologic alterations in patients with functionally univentricular hearts
1Division of Congenital Cardiac Surgery, Fortis Escorts Heart Research Institute, New Delhi, India.
Abstract:
Coagulation factor deficiencies may predispose patients with functionally univentricular hearts to bleeding tendencies preoperatively and perioperatively. Postoperatively, this is altered to a prothrombotic predisposition in these patients. Early and late thromboembolic events secondary to a prothrombotic state following univentricular repair contribute to significant morbidity after establishment of the Fontan circulation. Anticoagulation following univentricular repair is advocated but its benefits are controversial.
Related Concept Videos
Pathophysiology of Heart Failure
Heart Failure II: Pathophysiology
Cardiomyopathy II: Dilated Cardiomyopathy
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Heart Failure I: Introduction

